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In this trial, we showed that, compared with isCGM, rtCGM improved time in range and HbA1c, and increased the detection of hypoglycaemia and time spent in a safe range. Compared with isCGM, rtCGM increased the detection of hyperglycaemia, and the patients in the rtCGM group reported better quality of life and a better experience with rtCGM. The rtCGM group also tended to have a higher proportion of people who were physically active more than twice a week at 6 months of treatment.
Type 1 diabetes is a chronic condition in which the patient's own immune system destroys the β-cells of the pancreas. These cells produce insulin that is needed to control blood glucose levels in the blood. In order to keep blood glucose levels within the target range, people with type 1 diabetes need to test their blood glucose levels frequently and adjust insulin doses accordingly. This is a time-consuming and inconvenient process for people with type 1 diabetes. In addition, it is known that people with type 1 diabetes have limited awareness of hypoglycaemia or hyperglycaemia. Some people also suffer from long-term diabetes complications such as microvascular complications that often develop after years of disease, as well as macrovascular complications such as stroke, cardiovascular disease, and peripheral arterial disease that affect people with type 1 diabetes for the rest of their lives. People with type 1 diabetes also have a higher risk of premature mortality than the general population.
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